Publications 2009 (in alphabetic order of first author)
Van Ampting MTJ, Rodenburg W, Vink C, Kramer E, Schonewille AJ, Keijer J, van der Meer R, Bovee-Oudenhoven IMJ (2009) Ileal mucosal and fecal pancreatitis associated protein levels reflect severity of Salmonella infection in rats.
Digestive Disease Science, DOI 10.1007/s10620-008-0685-0
Anastasiadi M, Zira A, Magiatis P, Haroutounian SA, Skaltsounis AL, Mikros E.
1H NMR-based metabonomics for the classification of Greek wines according to variety, region, and vintage. Comparison with HPLC data.
J Agric Food Chem. 2009 Dec 9;57(23):11067-74.
Appeldoorn MM, Venema DP, Peters HTF, Koenen ME, Arts ICW, Vincken J-P, Gruppen H, Keijer J, Hollman PCH (2009)
Some phenolic compounds increase the nitric oxide level in endothelial cells in vitro.
Journal of Agricultural Food Chemistry 57:7693-7699.
Arola L, Bonet ML, Delzenne N, Duggal MS, Gómez-Candela C, Huyghebaert A, Laville M, Lingström P, Livingstone B, Palou A, Picó C, Sanders T, Schaafsma G, van Baak M, van Loveren C, van Schothorst EM.
Summary and general conclusions/outcomes on the role and fate of sugars in human nutrition and health.
Obes Rev. 2009 Mar;10 Suppl 1:55-8. No abstract available. PMID: 19207536
Balwierz A, Polus A, Razny U, Wator L, Dyduch G, Tomaszewska R, Scherneck S, Joost H, Dembinska-Kiec A.
Angiogenesis in the New Zealand obese mouse model fed with high fat diet.
Lipids in Health and Disease 2009, 8-13
Del Bas JM, Ricketts ML, Vaqué M, Sala E, Quesada H, Ardevol A, Salvadó MJ, Blay M, Arola L, Moore DD, Pujadas G, Fernandez-Larrea J, Bladé C.
Dietary procyanidins enhance transcriptional activity of bile acid-activated FXR in vitro and reduce triglyceridemia in vivo in a FXR-dependent manner.
Mol Nutr Food Res. 2009 Jul;53(7):805-14.PMID: 19496086
Blay M, Espinel AE, Delgado MA, Baiges I, Bladé C, Arola L, Salvadó J.
Isoflavone effect on gene expression profile and biomarkers of inflammation.
J Pharm Biomed Anal. 2010 Jan 20;51(2):382-90. Epub 2009 Apr 5.PMID: 19410411
Bosy-Westphal A, Müller MJ, Boschmann M, Klaus S, Kreymann G, Lührmann PM, Neuhäuser-Berthold M, Noack R, Pirke KM, Platte P, Selberg O, Steiniger J.
Grade of adiposity affects the impact of fat mass on resting energy expenditure in women.
Br J Nutr. 2009 Feb;101(4):474-7. PubMed PMID: 19230079.
Cannon B, Nedergaard J.
Thermogenesis challenges the adipostat hypothesis for body-weight control.
Proc Nutr Soc. 2009 Nov;68(4):401-7. Epub 2009 Sep 24. PMID:19775494
Chacón MR, Ceperuelo-Mallafré V, Maymó-Masip E, Mateo-Sanz JM, Arola L, Guitiérrez C, Fernandez-Real JM, Ardèvol A, Simón I, Vendrell J.
Grape-seed procyanidins modulate inflammation on human differentiated adipocytes in vitro.
Cytokine. 2009 Aug;47(2):137-42. Epub 2009 Jun 27.PMID: 19560935 [PubMed - indexed for MEDLINE]
O'Donoghue N, Sweeney T, Donagh R, Clarke KJ, Porter RK.
Control of choline oxidation in rat kidney mitochondria.
Biochim Biophys Acta. 2009 Sep;1787(9):1135-9. Epub 2009 May 6. PMID: 19426704 [PubMed - indexed for MEDLINE
Edgar D, Shabalina I, Camara Y, Wredenberg A, Calvaruso MA, Nijtmans L, Nedergaard J, Cannon B, Larsson NG, Trifunovic A. Random point mutations with major effects on protein-coding genes are the driving force behind premature aging in mtDNA mutator mice.
Cell Metab. 2009 Aug;10(2):131-8. PMID: 19656491
FEILLET-COUDRAY C., SUTRA T., FOURET G., RAMOS J., WRUTNIAK-CABELLO C., CABELLO G., CRISTOL J.P., COUDRAY C., 2009.
Oxidative stress in rats fed a high-fat high sucrose diet and preventive effect of polyphenols: involvement of mitochondrial and NAD(P)H oxidase system.
Free Radic. Biol. Med., 46, 624-632.
Feldmann HM, Golozoubova V, Cannon B, Nedergaard J.
UCP1 ablation induces obesity and abolishes diet-induced thermogenesis in mice exempt from thermal stress by living at thermoneutrality.
Cell Metab. 2009 Feb;9(2):203-9. PMID:19187776
FIGUEIREDO D., GERTLER A., CABELLO G., DECUYPERE E., BUYSE J., DRIDI S., 2007.
Leptin down regulates heat shock protein-70 (HSP70) gene expression in chicken liver and hypothalamus.
Cell Tissue Res., 329, 91-101.
Flachs P, Rossmeisl M, Bryhn M, Kopecky J.
Cellular and molecular effects of n-3 polyunsaturated fatty acids on adipose tissue biology and metabolism.
Clin Sci (Lond). 2009 Jan;116(1):1-16. Review.PMID: 19037880 [PubMed - indexed for MEDLINE]
Gratze P, Boschmann M, Dechend R, Qadri F, Malchow J, Graeske S, Engeli S, Janke J, Springer J, Contrepas A, Plehm R, Klaus S, Nguyen G, Luft FC, Muller DN.
Energy metabolism in human renin-gene transgenic rats: does renin contribute to obesity?
Hypertension. 2009 Mar;53(3):516-23. Epub 2009 Jan 26. PubMed PMID: 19171793.
Greaves LC, Mathers JC, Taylor RW, Turnbull DM.
Modelling mitochondrial DNA mutations in bacterial cytochrome c oxidase: link to colon cancer?
Proc Natl Acad Sci U S A. 2009 Jun 2;106(22):E57. Epub 2009 May 15. No abstract available. PMID: 19447926 [PubMed - indexed for MEDLINE]
Greaves LC, Beadle NE, Taylor GA, Commane D, Mathers JC, Khrapko K, Turnbull DM.
Quantification of mitochondrial DNA mutation load.
Aging Cell. 2009 Sep;8(5):566-72. Epub 2009 Jul 18.PMID: 19624578 [PubMed - indexed for MEDLINE]
Hamer I, Delaive E, Dieu M, Abdel-Sater F, Mercy L, Jadot M, Arnould T.
Up-regulation of cathepsin B expression and enhanced secretion in mitochondrial DNA-depleted osteosarcoma cells.
Biol Cell. 2009 Jan;101(1):31-41.
Hartwig K, Heidler T, Moch J, Daniel H, Wenzel U.
Feeding a ROS-generator to Caenorhabditis elegans leads to increased expression of small heat shock protein HSP-16.2 and hormesis.
Genes Nutr. 2009 Mar;4(1):59-67. Epub 2009 Feb 28.
Hartwich J., Malczewska-Malec M., Partyka Ł., Perez-Martinez P., Marin C., Lopez-Miranda J., Tierney A.C., Mc Monagle J., Roche H.M., Defoort C., Wołkow P., Dembińska-Kieć A.
The effect of the plasma n-3/n-6 polyunsaturated fatty acid ratio 2 on the dietary LDL phenotype transformation – insights from the LIPGENE study.
Clin Nutr. 2009 ;28: 510-515
Heidler T, Hartwig K, Daniel H, Wenzel U.
Caenorhabditis elegans lifespan extension caused by treatment with an orally active ROS-generator is dependent on DAF-16 and SIR-2.1.
Biogerontology. 2009 Jul 14. [Epub ahead of print]
van Helden Y, Keijer J, Knaapen A, Heil S, Briedé J, van Schooten F, Godschalk R (2009).
Beta-carotene metabolites enhance inflammation induced oxidative damage in lung epithelial cells.
Free Radical Biology and Medicine 46:299-304.
van Helden YGJ, Keijer J, Heil SG, Picó C, Palou A, Oliver P, Munnia A, Briedé JJ, Peluso M, Franssen-van Hal NLW, van Schooten F-J, Godschalk RWL. (2009)
Beta-carotene affects oxidative stress related DNA damage in lung epithelial cells and in ferret lung.
Carcinogenesis, 30: 2070-2076.
Isken F, Klaus S, Petzke KJ, Loddenkemper C, Pfeiffer AF, Weickert MO.
Impairment of fat oxidation under high vs low glycemic index diet occurs prior to the development of an obese phenotype.
Am J Physiol Endocrinol Metab. 2009 Nov 24. [Epub ahead of print] PubMed PMID: 19934403.
Isken F, Weickert MO, Tschöp MH, Nogueiras R, Möhlig M, Abdelrahman A, Klaus S, Thorens B, Pfeiffer AF.
Metabolic effects of diets differing in glycaemic index depend on age and endogenous glucose-dependent insulinotrophic polypeptide in mice.
Diabetologia. 2009 Oct;52(10):2159-68. Epub 2009 Jul 31. PubMed PMID: 19644669.
Isken F, Klaus S, Osterhoff M, Pfeiffer AF, Weickert MO.
Effects of long-term soluble vs. insoluble dietary fiber intake on high-fat diet-induced obesity in C57BL/6J mice.
J Nutr Biochem. 2009 Apr 13. [Epub ahead of print] PubMed PMID: 19369060.
Keipert S, Klaus S, Heldmaier G, Jastroch M.
UCP1 ectopically expressed in murine muscle displays native function and mitigates mitochondrial superoxide production. Biochim Biophys Acta. 2009 Dec 1. [Epub ahead of print] PubMed PMID: 19958747.
Kieć-Wilk B., Kieć-Klimczak M., Dembińska-Kieć A.
Różnicowanie się komórek tkanki tłuszczowej a odpowiedź siateczki endoplazmatycznej (ER) i ich rola w ochronie przed zniszczeniem komórek beta trzustki oraz rozwojem cukrzycy typu 2. Role of preadipocytes differentiation and the endoplasmic reticulum (ER) stress in the protection of pancreatic beta-cells and development of diabetes type 2.
Czynniki Ryzyka 3/09 (60):3-15
Kipp A, Banning A, van Schothorst EM , Méplan C, Schomburg L, Evelo C, Coort S, Gaj S, Keijer J, Hesketh J, Brigelius-Flohé R (2009)
Four selenoproteins, protein biosynthesis, and Wnt signalling 1 are particularly sensitive to selenium intake in mouse colon. Molecular Food and Nutrition Research, 53:1561-1572.
Løvås K, Røst TH, Skorve J, Ulvik RJ, Gudbrandsen OA, Bohov P, Wensaas AJ, Rustan AC, Berge RK, Husebye ES. Tetradecylthioacetic acid attenuates dyslipidaemia in male patients with type 2 diabetes mellitus, possibly by dual PPAR-alpha/delta activation and increased mitochondrial fatty acid oxidation.
Diabetes Obes Metab. 2009 Apr;11(4):304-14. PMID: 19267708 4.
Melliou E, Michaelakis A, Koliopoulos G, Skaltsounis AL, Magiatis P.
High quality bergamot oil from Greece: Chemical analysis using chiral gas chromatography and larvicidal activity against the West Nile virus vector.
Molecules. 2009 Feb 18;14(2):839-49.
Montagut G, Bladé C, Blay M, Fernández-Larrea J, Pujadas G, Salvadó MJ, Arola L, Pinent M, Ardévol A.
Effects of a grapeseed procyanidin extract (GSPE) on insulin resistance.
J Nutr Biochem. 2009 Dec 3. [Epub ahead of print]PMID: 19962298 [PubMed - as supplied by publisher]
Montagut G, Onnockx S, Vaqué M, Bladé C, Blay M, Fernández-Larrea J, Pujadas G, Salvadó MJ, Arola L, Pirson I, Ardévol A, Pinent M.
Oligomers of grape-seed procyanidin extract activate the insulin receptor and key targets of the insulin signaling pathway differently from insulin.
J Nutr Biochem. 2009 May 13. [Epub ahead of print]PMID: 19443198 [PubMed - as supplied by publisher]
Murphy JE, Porter RK.
The control of oxidative phosphorylation in the adrenal gland (Y1) cell line.
Adv Exp Med Biol. 2009;645:35-41. PMID: 19227447 [PubMed - indexed for MEDLINE]
Nooteboom M, Johnson R, Taylor RW, Wright NA, Lightowlers RN, Kirkwood TB, Mathers JC, Turnbull DM, Greaves LC.
Age-associated mitochondrial DNA mutations lead to small but significant changes in cell proliferation and apoptosis in human colonic crypts.
Aging Cell. 2009 Oct 30. [Epub ahead of print]PMID: 19878146 [PubMed - as supplied by publisher]
van Ommen, B, Keijer J, Heil SG, Kaput J (2009)
Challenging homeostasis to define biomarkers for individual nutrition related health.
Molecular Nutrition and Food Research, 53: 795-804.
Palou A, Pico C, Keijer J (2009)
Integration of risk and benefit analysis - The window of benefit as a new tool?
Critical Reviews in Food Science and Nutrition, 49(7):670-680.
De Pauw A, Tejerina S, Raes M, Keijer J, Arnould T.
Mitochondrial (dys)function in adipocyte (de)differentiation and systemic metabolic alterations.
Am J Pathol. 2009: 175:927-739.
Petrovic N, Walden TB, Shabalina IG, Timmons JA, Cannon B, Nedergaard J.
Chronic PPAR Activation of Epididymally Derived White Adipocyte Cultures Reveals a Population of Thermogenically Competent, UCP1-containing Adipocytes Molecularly Distinct From Classical Brown Adipocytes.
J Biol Chem. 2009 Dec 22. PMID:20028987
Puiggròs F, Sala E, Vaqué M, Ardévol A, Blay M, Fernández-Larrea J, Arola L, Bladé C, Pujadas G, Salvadó MJ.
In vivo, in vitro, and in silico studies of Cu/Zn-superoxide dismutase regulation by molecules in grape seed procyanidin extract.
J Agric Food Chem. 2009 May 13;57(9):3934-42.PMID: 19317487 [PubMed - indexed for MEDLINE]
Quesada H, del Bas JM, Pajuelo D, Díaz S, Fernandez-Larrea J, Pinent M, Arola L, Salvadó MJ, Bladé C.
Grape seed proanthocyanidins correct dyslipidemia associated with a high-fat diet in rats and repress genes controlling lipogenesis and VLDL assembling in liver.
Int J Obes (Lond). 2009 Sep;33(9):1007-12. Epub 2009 Jul 7.PMID: 19581912 [PubMed - in process]
Razny U., Polus A., Kiec-Wilk B., Wator Ł., Hartwich J., Stachura J. Tomaszewska R., Dyduch G., Laidler p., Schmitz G., Goralczyk R., Wertz K., Riss G., Franssen-van Hal N.R.W., Keijer J., Dembinska-Kiec A.
Angiogenesis in Balb/c mice under beta-carotene supplementation in diet.
Genes Nutr. 2009 Nov 28. [Epub ahead of print]
Rokling-Andersen MH, Rustan AC, Wensaas AJ, Kaalhus O, Wergedahl H, Røst TH, Jensen J, Graff BA, Caesar R, Drevon CA. Marine n-3 fatty acids promote size reduction of visceral adipose depots, without altering body weight and composition, in male Wistar rats fed a high-fat diet.
Br J Nutr. 2009 Oct;102(7):995-1006. Epub 2009 Apr 28.PMID: 19397836 3.
Schepens MAA, Schonewille AJ, Vink C, van Schothorst EM, Kramer E, Hendriks T, Brummer R-J, Keijer J, van der Meer R, Bovee-Oudenhoven IMJ. (2009)
Supplemental calcium attenuates the colitis-related increase in diarrhea, intestinal permeability and extracellular matrix breakdown in HLA-B27 transgenic rat.
Journal of Nutrition, 139:1525-1533.
van Schothorst EM, Bunschoten A, Schrauwen P, Mensink RP, Keijer J (2009)
Effects of a high fat, low versus high glycemic index diet: retardation of insulin resistance involves adipose tissue modulation. FASEB J 23:1092-1101.
Van Schothorst EM, Flachs P, Franssen-van Hal NLW, Kuda O, Bunschoten JE, Molthoff J, Vink C, Hooiveld GJEJ, Kopecky J, Keijer J (2009)
Induction of lipid oxidation genes by polyunsaturated fatty acids of marine origin in small intestine of mice fed a high-fat diet. BMC genomics. 2009 Mar 16;10:110 PMID:19284886
Serra A, Macià A, Romero MP, Valls J, Bladé C, Arola L, Motilva MJ.
Bioavailability of procyanidin dimers and trimers and matrix food effects in in vitro and in vivo models.
Br J Nutr. :1-9. [Epub ahead of print]PMID: 20003617 [PubMed - as supplied by publisher]
Sliwa A., Balwierz A., Kiec-Wilk B., Polus A., Knapp A., Dembinska-Kiec A.
Differentiation of human adipose tissue SVF cells into cardiomyocytes
Genes Nutr. 2009 ; 4(3):195-198
Szopa M., Malczewska-Malec M., Kieć-Wilk B., Skupien J., Wolkow P., Malecki M.T., Sieradzki J.
Variants of the adiponectin gene and type 2 diabetes in a Polish population
Acta Diabetol (2009) 46:317–322
Szopa M., Malczewska-Malec M., Wybrańska I., Kieć-Wilk B. Warianty genu adiponektyny jako czynniki ryzyka zespołu metabolicznego.
Variants of adiponectin gene as risk factors for the metabolic syndrome.
Przegląd Lekarski, vol. 66(5), 2009: 257-262
Tejerina S, De Pauw A, Vankoningsloo S, Houbion A, Renard P, De Longueville F, Raes M, Arnould T.
Mild mitochondrial uncoupling induces 3T3-L1 adipocyte de-differentiation by a PPARgamma-independent mechanism, whereas TNFalpha-induced de-differentiation is PPARgamma dependent.
J Cell Sci. 2009 Jan 1;122(Pt 1):145-55. Epub 2008 Dec 9.
Terra X, Fernández-Larrea J, Pujadas G, Ardèvol A, Bladé C, Salvadó J, Arola L, Blay M.
Inhibitory effects of grape seed procyanidins on foam cell formation in vitro.
J Agric Food Chem. 2009 Mar 25;57(6):2588-94.PMID: 19292475 [PubMed - indexed for MEDLINE]
Terra X, Montagut G, Bustos M, Llopiz N, Ardèvol A, Bladé C, Fernández-Larrea J, Pujadas G, Salvadó J, Arola L, Blay M. Grape-seed procyanidins prevent low-grade inflammation by modulating cytokine expression in rats fed a high-fat diet.
J Nutr Biochem. 2009 Mar;20(3):210-8. Epub 2008 Jul 7.PMID: 18602813 [PubMed - indexed for MEDLINE]
Tourniaire F, Gouranton E, von Lintig J, Keijer J, Bonet ML, Amengual J, Lietz G, Landrier JF (2009)
β-carotene conversion products and their effects on adipose tissue.
Genes and Nutrition, 4:179-187.
Valls J, Millán S, Martí MP, Borràs E, Arola L.
Advanced separation methods of food anthocyanins, isoflavones and flavanols.
J Chromatogr A. 2009 Oct 23;1216(43):7143-72. Epub 2009 Jul 21. Review.PMID: 19691963 [PubMed - indexed for MEDLINE]
Walden TB, Timmons JA, Keller P, Nedergaard J, Cannon B.
Distinct expression of muscle-specific microRNAs (myomirs) in brown adipocytes.
J Cell Physiol. 2009 Feb; 218(2): 449-9. PMID: 18937285
Wensaas AJ, Rustan AC, Rokling-Andersen MH, Caesar R, Jensen J, Kaalhus O, Graff BA, Gudbrandsen OA, Berge RK, Drevon CA.
Dietary supplementation of tetradecylthioacetic acid increases feed intake but reduces body weight gain and adipose depot sizes in rats fed on high-fat diets.
Diabetes Obes Metab. 2009 Nov;11(11):1034-49. Epub 2009 Sep 9.PMID: 19740081 2.
Wensaas AJ, Rustan AC, Just M, Berge RK, Drevon CA, Gaster M.
Fatty acid incubation of myotubes from humans with type 2 diabetes leads to enhanced release of beta-oxidation products because of impaired fatty acid oxidation: effects of tetradecylthioacetic acid and eicosapentaenoic acid.
Diabetes. 2009 Mar;58(3):527-35. Epub 2008 Dec 9.PMID: 19066312
Wybrańska I. Genetyczne uwarunkowania otyłości i jej wybranych następstw w grupie rodzin otyłych z terenu małopolski.
„The genetic background of obesity and its consequences in obese families from Malopolska region”.
Rozprawy Habilitacyjne Uniwersytetu Jagiellońskiego CM UJ.
Wydział Lekarski. Wydawnictwo Uniwersytetu Jagiellońskiego., 2008: 11-238
Xue Y, Petrovic N, Cao R, Larsson O, Lim S, Chen S, Feldmann HM, Liang Z, Zhu Z, Nedergaard J, Cannon B, Cao Y.
Hypoxia-independent angiogenesis in adipose tissues during cold acclimation.
Cell Metab. 2009 Jan 7;9(1):99-109. PMID: 19117550
Zingaretti MC, Crosta F, Vitali A, Guerrieri M, Frontini A, Cannon B, Nedergaard J, Cinti S.
The presence of UCP1 demonstrates that metabolically active adipose tissue in the neck of adult humand truly represents brown adipose tissue.
FASEB J. 2009 Sep;23(9):3113-20. Epub 2009 May 5. PMID: 19417078