Rolf Berge

Prof. dr. Rolf Berge
Institute of Medicine, Section of Medical Biochemistry
The Lipid Research Group, University of Bergen
Haukeland University Hospital
N-5021 Bergen
NORWAY
Tel +47 5597 3098
Fax +47 5597 3115
E-mail: rolf.berge@ikb.uib.no


Expertise:
Influence of bioactive components (lipids, modified fatty acids and peptides) on PPAR-dependent and -independent pathways including mitochondrial function on metabolic syndrome and cell death


Relevant projects and functions:

• Partner in the EU-FP6 integrated project LIPGENE
• Member of the ICBL Steering Committee
• Founder of the biotechnological company Thia Medica

Group structure:
1 Professor (M), 2 senior scientists (M), 2 post-docs (1 M, 1 F), 2 PhD students (F), 5 technicians (F)


Selected publications:
1. Grav HJ, Tronstad KJ, Gudbrandsen OA, Berge K, Fladmark KE, Martinsen TC, Waldum H, Wergedahl H, Berge RK. 2003. Changed energy state and increased mitochondrial beta-oxidation rate in liver of rats associated with lowered proton electrochemical potential and stimulated uncoupling protein 2 (UCP-2) expression: evidence for peroxisome proliferator-activated receptor-alpha independent induction of UCP-2 expression. J Biol Chem 278: 30525-33
2. Tronstad KJ, Gjertsen BT, Krakstad C, Berge K, Brustugun OT, Doskeland SO, Berge RK. 2003. Mitochondrial-targeted fatty acid analog induces apoptosis with selective loss of mitochondrial glutathione in promyelocytic leukemia cells. Bhem Biol 10: 609-18

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