Prof. John C. Mathers
Human Nutrition Research Centre
Institute for Ageing and Health
Newcastle University
NE2 4HH
UNITED KINGDOM
Website: http://www.ncl.ac.uk/hnrc/people/profile/john.mathers
Expertise:
Molecular mechanisms linking nutrition with human health including role of mitochondrial defects in ageing and in the aetiology of bowel cancer.
Relevant projects and functions:
Studies of the impact of nutrition on brain ageing through the Centre for Brain Ageing and Vitality.
See: http://www.ncl.ac.uk/biomedicine/research/centres/cbav.htm
Group structure:
4 Post-docs, 5 research students, 2 technicians, 2 administrative officers (in total: 5 male, 9 female)
Selected publications:
Defects in multiple complexes of the respiratory chain are present in ageing human colonic crypts. Greaves LC, Barron MJ, Plusa S, Kirkwood TB, Mathers JC, Taylor RW, Turnbull DM. Exp Gerontol. 2010 Jan 22. (Epub ahead of print) PMID: 20096767
Age-associated mitochondrial DNA mutations lead to small but significant changes in cell proliferation and apoptosis in human colonic crypts. Nooteboom M, Johnson R, Taylor RW, Wright NA, Lightowlers RN, Kirkwood TB, Mathers JC, Turnbull DM, Greaves LC. Aging Cell. 2010 Feb;9(1):96-9. Epub 2009 Oct 30. PMID: 19878146